Wednesday, 26 August 2020

Moderna Covid vaccine appears to work as well in older adults: Study

The latest data from an early Phase I study includes an analysis from 20 additional people detailing how the vaccine performed in older adults
Coronavirus, vaccine, covid, drugs, tests, clinical trials
International News: (Reuters) – Moderna Inc said on Wednesday its experimental COVID-19 vaccine induced immune responses in older adults similar to those in younger participants, offering hope that it will be effective in people considered to be at high risk for severe complications from the coronavirus.
The company is one of the leading contenders in the race to develop a vaccine against the virus that has killed more than 820,000 people worldwide. Its candidate, mRNA-1273, is already in late-stage human trials testing its ability to safely prevent infection. The latest data from an early Phase I study includes an analysis from 20 additional people detailing how the vaccine performed in older adults.
The analysis looked at subjects given the 100-microgram dose being tested in the much larger Phase III trial. Moderna said the immune responses in those aged between ages 56 and 70, above age 70 and those 18 to 55-years-old were similar. Health officials have been concerned about whether Corona vaccine candidates would work in older people, whose immune systems typically do not respond as strongly to vaccines.


Moderna shares, which have more than tripled in value this year, rose about 6% after the data’s release. The company has so far enrolled over 13,000 participants in its late-stage study. About 18% of the total participants are Black, Latino, Native American or Alaska Native, groups that have been particularly hard hit by the pandemic, and are often under represented in clinical trials…

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