Mahesh Bhatt’s ‘Sadak 2’ gets a release date

Mahesh Bhatt is all set to make a remake of his 1991 superhit movie, ‘Sadak’ and the flick will hit the theatres on November 15, 2019.

Confirming the news, film critic and trade analyst took to Twitter and wrote,”IT’S OFFICIAL… #Sadak2 to release on 15 Nov 2019… Lead cast and other details will be announced shortly… Produced by Mukesh Bhatt… Mahesh Bhatt in association with Vishesh Films presents the film.”

The 1991 blockbuster starred Sanjay Dutt, Pooja Bhatt, Sadashiv Amrapurkar, Deepak Tijori and Neelima Azeem.

The movie was based on the life of a young man who falls in love with a sex worker. He was forced to overcome the social stigma as well as face the brothel owner and some criminal elements…Read More

3 in 5 babies not breastfed in first hour of life

According to United Nations Children’s Fund (UNICEF) and World Health Organization (WHO), around 78 million babies or three in every five are not breastfed within the first hour of the birth, putting them at a higher risk of death and disease and making them less likely to continue breastfeeding.

Most of these babies are born in low- and middle-income countries.

According to the report, newborns who breastfeed in the first hour of life are significantly more likely to survive. Even a delay of a few hours after birth could pose life-threatening consequences.

ALSO READ : Anti-bodies that fight Ebola viruses are now a reality

It should be noted that skin-to-skin contact along with suckling at the breast stimulates the mother’s production of breast milk, including colostrum, also called the baby’s ‘first vaccine’, which is extremely rich in nutrients and antibodies.

UNICEF Executive Director Henrietta H. Fore said, “When it comes to the start of breastfeeding, timing is everything. In many countries, it can even be a matter of life or death,” adding, “Yet each year, millions of newborns miss out on the benefits of early breastfeeding and the reasons – all too often – are things we can change. Mothers simply don’t receive enough support to breastfeed within those crucial minutes after birth, even from medical personnel at health facilities.”

>>>READ MORE<<<

Anti-bodies that fight Ebola viruses are now a reality

Finally, anti-bodies to three major Ebola viruses have now been developed.

Researchers at Vanderbilt University Medical Center are a step closer to developing a broadly effective antibody treatment against these viruses that cause the lethal disease in humans.

Researchers found that the isolation of two potent monoclonal antibodies from human survivors of Ebola virus disease in cell culture studies efficiently neutralized the Zaire, Sudan and Bundibugyo Ebola viruses.

ALSO READ : 3 in 5 babies not breastfed in first hour of life

The antibodies, EBOV-515 and EBOV-520, also showed the capacity to protect against infection by these viruses in animal models.

Researchers said further study is needed as these antibodies could lead to development of injectable antibody “cocktails” for people at high risk of being infected by Ebola viruses.

>>>READ MORE<<<

Hair loss gene is key to improved cancer immunotherapy

Harnessing the gene behind hair loss could help improve cancer immunotherapy.

A study by Columbia University Irving Medical Center researchers confirmed the possibility.

“While immunotherapies have shown great promise in cancer, most patients do not benefit from these treatments because their tumours are able to evade the immune system,” said a lead researcher, Angela M. Christiano.

Also Read : 3 in 5 babies not breastfed in first hour of life

“But one way around this obstacle is to harness genes that cause the recruitment of T cells in autoimmune disease and use them to attract T cells to kill tumours. In this study, we showed that a gene that recruits T cells in alopecia areata- a condition in which immune cells attack and destroy hair cells–is turned off in various types of cancer, protecting them from the immune system. But if we turn that gene back on, we can make those cancers vulnerable to the immune response,” he added.

The study began with the recognition that auto-immune diseases and cancer represent opposite ends of the immune signalling spectrum.

When the immune system is overactive, a patient may be at risk for auto-immune disease; when it’s underactive, cancer can evade the immune system and progress.

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Football effective for old diabetic patients

Turns out, playing football helps increase the bone strength of diabetic patients (male and female) between 55 to 70 years.

Individuals with prediabetes and type-2 diabetes have a higher prevalence of osteopenia. A recent study confirmed that football is effective for osteogenic training and that it has significant positive effects in the legs and clinically important femoral sites.

In the study, Dual-energy X-ray absorptiometry (DXA) scans were used t evaluate the initial bone health of the participants as well as the training-induced effects, along with blood samples to determine plasma markers for bone turnover and bone formation.

Also Read : Hair loss gene is key to improved cancer immunotherapy

From these measurements, 73 percent of the participants were diagnosed with femoral osteopenia and 24 percent with femoral osteoporosis prior to the intervention.

After 16 weeks of training, between-group changes in favour of football training were observed for the bone mineral content of the femoral neck (3.2 percent) and femoral shaft (2.5 percent) as well as for bone mineral content (32 g). Plasma osteocalcin and P1NP were elevated in the football group by 23 percent and 52 percent respectively, with greater changes than in the control group.

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Bill seeking death penalty for child rape passed: Things you should know

According to the new bill, there will be stringent punishment for rapists of girls under 12

The Lok Sabha on Monday passed the Criminal Law (Amendment) Bill 2018, which will allowsthe death penalty to those convicted of raping girls below the age of 12.

The bill seeks to replace an ordinance promulgated by the government in April after an outcry over the rape and murder of an eight-year-old girl in Kathua in Jammu & Kashmir.

The Criminal Law (Amendment) Bill 2018 was supported by most members across the political spectrum and passed by a voice vote, PTI reported. Minister of State for Home Kiren Rijiju said, “The stringent law was aimed at providing safety to minor girls.”

Here are few things you should know about the Bill:

1. According to the new bill, there will be stringent punishment for rapists of girls under 12. The punishment for rape of a woman aged under 12 years will be rigorous imprisonment of at least 20 years but may extend to imprisonment for life or death.

2. The minimum punishment in cases of rape of women has been increased from the rigorous imprisonment of seven years to 10 years, extendable to life imprisonment.

3. According to the bill, in case of rape of a girl under 16 years, the minimum punishment has been increased from 10 to 20 years, extendable to imprisonment for rest of life.

4. The punishment for the gangrape of a girl below 16 years will invariably be imprisonment for the rest of life of the convict.

(READ FULL STORY)

Brain reward response may impact anorexia nervosa

A new study has found that the brain’s response to taste stimuli is linked to high anxiety and a drive for thinness that could play a role in driving anorexia nervosa.

The researchers, led by Dr. Guido Frank, MD, associate professor of psychiatry and neuroscience at the University Of Colorado School Of Medicine, monitored a large group of patients with anorexia nervosa as they tasted sugar during brain imaging.

Frank found that as these patients restricted their diet, a brain reward circuit associated with the neurotransmitter dopamine becomes more active but also triggers anxiety. This makes food avoidance worse and perpetuates the often deadly disease.

ALSO READ : E-cigarettes, tobacco linked to higher risk of oral cancer

The researchers found their brain response was higher than those in the control group, representing a biological marker for the illness. At the same time, this brain response was related to high anxiety and less weight gain for those being treated for anorexia nervosa.

“When you lose weight your brain reward response goes up,” said Frank. “But instead of driving eating, we believe it elevates anxiety in anorexia nervosa, which makes them want to restrict more. This becomes then a vicious cycle.”…READ SOURCE

New genes linked to childhood nephrotic syndrome identified

Childhood nephrotic syndrome is one of the most common chronic kidney diseases among children.

A Japanese research team led by Professor Kazumoto Iijima, Associate Professor Kandai Nozu and Tomoko Horinouchi, identified a group of genes which are strongly related to the development of childhood nephrotic syndrome.

Also known as nephrosis, childhood nephrotic syndrome is an incurable disease with an unknown cause, characterised by large amounts of protein leaving the body in the patient’s urine, and protein levels in the bloodstream becoming extremely low.

The majority of patients develop a steroid-sensitive nephrotic syndrome that responds to steroids and immune-suppressing drugs and go into remission, but at least 20% of cases are resistant strains that recur repeatedly during adulthood.

It is found that people who are genetically predisposed develop the syndrome when exposed to an immunological stimulus such as infection.

The research team is currently carrying out a genome-wide association study using the Japonica Array that targets 1,152 samples from infant nephrotic syndrome sufferers and a control group of 2,807 healthy Japanese individuals….READ MORE

Scuba diving risky for older hearts

Turns out, overweight scuba divers are being urged to shed pounds to avoid an underwater heart attack.

A new study conducted by the researchers of European Society of Cardiology found that aged and corpulent scuba divers are at a risk of an underwater heart attack.

“Cardiac issues are now a leading factor in diving fatalities. Divers who learned to dive years ago and who are now old and overweight, with high blood pressure and high cholesterol, are at increased risk of dying,” said study author Dr Peter Buzzacott.

Also read : Brain reward response may impact anorexia nervosa

People who pay to go diving must learn skills and theory and be screened for fitness. After that initial screening, certification to scuba dive lasts for life. This is where the researchers see an increase in risk. It’s not commonly new divers who have health problems, because they have been recently screened. It is older divers who have not looked after their health.

Until now, there has been no clear picture of how common cardiovascular risk factors are among active divers.

This analysis compared the 113,892 scuba divers with a group of 338,933 active people matched for age, sex, and state of residence whose main activity was not scuba diving. The data shows that one-third of scuba divers are aged 50 years or older.

>>>READ STORY<<<

E-cigarettes, tobacco linked to higher risk of oral cancer

Turns out, Tobacco use remains a leading cause of oral cancer but the tobacco landscape is evolving with increasing use of non-cigarette tobacco products and dual-use of multiple product types.

Benjamin Chaffee and co-author Neal Benowitz, University of California, evaluated exposure to known carcinogens (a substance capable of causing cancer in living tissue) according to recent use of different tobacco product types, alone or in combination.

Participants were categorized according to use of combustible, which includes cigarettes, cigars, water pipe, pipes, blunts (marijuana-containing cigars), smokeless, which includes moist snuff, chewing tobacco and snus, e-cigarettes and nicotine replacement products.

For each product, the recent use was defined as within the prior three-days and non-use defined as none within 30-days.

All tobacco use categories demonstrated elevated nicotine and tobacco-specific nitrosamines (TSNAs) concentrations relative to non-users. TSNA exposures were highest among smokeless tobacco users, whether used or together with other product types.

Most e-cigarette users concurrently used combustible tobacco resulting in TSNA exposure similar to exclusive cigarette smokers.

The analysis shows that the vast majority of non-cigarette tobacco users are exposed to carcinogen levels comparable to or exceeding exposure among exclusive cigarette smokers, levels that are likely to place users at substantial risk….READ SOURCE

Katrina Kaif to star opposite Salman after Priyanka’s ‘Bharat’ exit

Director Ali Abbas Zafar has found his new female lead in Katrina Kaif, days after Priyanka Chopra’s departure from “Bharat”.

The film, to be released Eid next year, reunites Salman Khan and Katrina after 2017 blockbuster “Tiger Zinda Hai”, which was also directed by Ali.

The director is excited to reteam with the actor duo.

“I am extremely excited to work with Katrina Kaif and Salman Khan once again for Bharat. We have had exciting collaborations in the past and it is very interesting to work with the duo once again.

“Katrina got on board in the Nick of time for the project and it is very delightful to work with the immensely talented actress yet again,” Ali said in a statement.

Katrina will be joining the shoot in the upcoming schedules beginning in September.

The announcement comes after the director took to Twitter to reveal that Priyanka had left “Bharat” due to a “very special” reason.

Ali did not elaborate much on the “reason” but his tweet alluded the actor’s exit to her rumoured romance with American singer, Nick Jonas.

The film recently went on floors with Salman and actor Disha Patani.

Ali had shared recently a sneak peek from the film that showed Salman entering a “ring of fire” on a bike in a circus…READ MORE

Physical activities can reduce risk of cancer

A healthy diet and physical activities with no alcohol consumption can help in reducing overall cancer risk besides also lowering breast, prostate and colorectal cancer risks.

Researchers at the American Association for Cancer Research analysed the nutritional scores which showed the biggest benefit from a diet that discourages alcohol and reduces the risk of cancer.

The researchers estimated that in developed countries, around 35 per cent of breast cancers and 45 per cent of colorectal cancers could be avoided by better adherence to nutritional recommendations. It is, therefore, very important to investigate the role of nutrition in cancer prevention.

This study evaluated three previously validated nutritional recommendations: The WCRF/AICR score; the Alternate Healthy Eating Index; and the French Nutrition and Health Program-Guidelines Score, plus one relatively new index, the MEDI-LITE score, which measures adherence to a Mediterranean diet. Researchers found that all the diets were associated with some reduced risk, but the WCRF/AICR recommendations, developed specifically with cancer prevention in mind, had the strongest association with reduced risk…READ MORE

Pollution can change wildlife behaviour

With an increasing number of factors affecting the animal behaviour, the field of behavioural toxicology is gaining traction within the environmental sciences.

A team of scientists from the University of Portsmouth has developed new scientific tests to better understand the effects of pollution on wildlife behaviour.

An organism’s behaviour is fundamentally important to their survival through feeding, finding mates and escaping predators. Any chemical which could interfere with these responses has the potential to impact the food chain.

Using small shrimp-like crustaceans called amphipods, which are commonly used to monitor environmental toxicology, the researchers have been designing experiments to best answer the questions.

In previously determining that these animals prefer to swim away from the light (negative phototaxis) and preferably be touching the sides of the tanks (positive thigmotaxis), they first set about asking whether these preferences could be altered by the size and shape of their testing tanks..READ MORE

‘Saheb, Biwi Aur Gangster 3’: Convoluted and trite (IANS Review, Rating: **)

Film: “Saheb Biwi Aur Gangster 3”; Director: Tigmanshu Dhulia; Cast: Sanjay Dutt, Jimmy Sheirgill, Mahie Gill, Zakir Hussain, Deepak Tijori, Nafisa Ali, Kabir Bedi, Chitrangada Singh; Rating: **

The third edition of Director Tigmanshu Dhulia’s Saheb, Biwi Aur Gangster 3, once again revolves around its central characters, Saheb’s first wife, Madhavi Devi (Mahie Gill) and Saheb aka Aditya Pratap Singh (Jimmy Sheirgill) plotting and planning to oust and eliminate each other in their quest for power and supremacy. Clearly there is no love lost between them.

Yuvraj Uday Singh (Sanjay Dutt), from another royal family, is a notorious gangster and a Russian Roulette expert, who is shunted away to London after he commits a murder. Upon his return, he too finds himself in the midst of a family which is playing games with him in a bid to have him removed from the scene.

A convoluted plot of treachery, deceit and lust, unfolds over a period of two hours plus, where each character tries to outdo and outsmart the other cleverly in this noir drama.

The setting in an opulent haveli in Boondigarh, in Rajasthan, remains the same and so do the central characters with the exception of Sanjay Dutt, who is a new addition as the gangster Baba. How the lives of the three central characters get intertwined and the unexpected twist in their intended plan, is what propels the film forward.

CLICK HERE  : SAHEB BIWI AUR GANGSTER 3 REVIEW

Mind-body therapies can help teens with anxiety

Turns out, biofeedback, mindfulness, yoga, and hypnosis provide a promising approach to the very common problem of anxiety in adolescents.

Researchers at Wolters Kluwer Health stated that the currently recommended treatments for adolescent anxiety i.e. cognitive behavioral therapy and antidepressant medications have important limitations.

Anxiety and fear are typical reactions to the academic, social, and developmental challenges that are common during the adolescent years. Clinical or pathological anxiety is excessive, persistent, and disruptive. While anxiety is often situational and time-limited, many teens develop chronic anxiety lasting six months or longer.

Mind-body therapies encompass self-regulation and positive thinking to help promote self-control, physical health, and emotional well-being.

Biofeedback techniques enable individuals to increase self-awareness and physical control through feedback on biological measures whereas mindfulness techniques incorporate aspects of meditation, body scanning…CLICK HERE

Immune system may cure Alzheimer’s disease

Turns out, vessels connecting the brain and the immune system play critical roles in both Alzheimer’s disease and decline in cognitive ability that comes with time.

Scientists at the University of Virginia improved the function of the lymphatic vessels to dramatically enhance the ability of aged people to learn and improve their memories.

Lymphatic vessels are a network of tiny, thin-walled vessels which are designed to pick up the fluid that leaks into the tissues from the bloodstream and return it to the circulatory system.

The researchers used a compound to improve the flow of waste from the brain to the lymph nodes in the neck of aged mice. The vessels became larger and drained better, and that had a direct effect on the ability to learn and remember.

They also determined that obstructing the vessels worsens the accumulation of harmful amyloid plaques in the brain that are associated with Alzheimer’s disease…READ FULL STORY

Feeling faint while standing up linked with dementia risk: Study

Any sudden drop in blood pressure in middle-aged people, which makes them feel faint, dizzy or light-headed while standing up, could be a sign of increased risk of dementia or stroke later, say researchers.

The findings suggested that people who experienced the blood pressure drop — known as orthostatic hypotension — had a 54 per cent higher risk of developing dementia.

They were also found to be at two times higher risk of developing ischemic stroke, which occurs when a blood vessel carrying blood to the brain is blocked by a blood clot.

“Orthostatic hypotension has been linked to heart disease, fainting and falls, so we wanted to conduct a large study to determine if this form of low blood pressure was also linked to problems in the brain, specifically dementia,” said Andreea Rawlings, from the Johns Hopkins University in Maryland, US.

For the study, published in the journal Neurology, the team analysed data from 11,709 people with an average age of 54 years, who were followed for an average of 25 years.

The participants were instructed to lie down for 20 minutes and then stand up in a smooth, swift motion….READ FULL STORY

PeeCee quits ‘Bharat’ in ‘Nick’ of time, hints marriage

Director Ali Abbas Zafar confirmed the news on Twitter stating that the actress has opted out from the flick owing to a very “special reason”.

Global sensation Priyanka Chopra is no more a part of Salman Khan starrer ‘Bharat’.

Director Ali Abbas Zafar confirmed the news on Twitter stating that the actress has opted out from the flick owing to a very “special reason”.

He wrote, “Yes Priyanka Chopra is no more part of @Bharat_TheFilm & and the reason is very very special, she told us in the Nick of time about her decision and we are very happy for her … Team Bharat wishes @priyankachopra loads of love & happiness for life.”

The director seemed to be hinting Priyanka’s marriage with rumoured boyfriend and singer Nick Jonas as he mentioned “Nick” of time in his tweet.

On a related note, ‘Bharat’ will feature Salman sporting five different looks spanning 60 years. The actor will be recreating his ‘Maine Pyaar Kiya’ look in the movie which has created immense excitement amongst the audience.

Meanwhile, the ‘Quantico’ star is already shooting for Shonali Bose’s upcoming directorial ‘The Sky Is Pink’ with Farhan Akhtar and Zaira Wasim….READ MORE STORY

Imran Khan claims victory amid poll tampering charges in Pakistan

Khan’s Pakistan Tehreek-e-Insaf emerged as the single largest in the National Assembly with its candidates winning 104 seats and leading in 14 others

Pakistan Tehreek-e-Insaf chief Imran Khan on Thursday claimed victory in the general elections after his party emerged as the single largest in the National Assembly with its candidates winning 104 seats and leading in 14 others, amid rival political parties’ claim of “blatant” rigging.

Jailed former prime minister Nawaz Sharif’s Pakistan Muslim League-Nawaz (PML-N) won 58 seats and was leading on four, while Pakistan Peoples Party (PPP) led by former president Asif Ali Zardari won 37 seats and was leading on six, according to the latest unofficial results.

Also Read : Captain Imran Khan faces many challenges on Pakistan economy front

Pakistan’s National Assembly comprises a total of 342 members, of which 272 are directly elected whereas the rest – 60 seats reserved for women and 10 for religious minorities – are selected later through proportional representation among parties with more than 5 per cent of the vote. A party can only form the government if it manages to clinch 172 seats in total.

“After a 22-year-long struggle, the almighty God has finally given me the chance to implement the manifesto I had dreamed up over two decades ago,” Khan, 65, said in his first public address after the polls.

Click Here : Imran khan

Masala entertainers encouraged Ranveer Singh to become an actor

He has played myriad roles ever since his Bollywood debut in 2010 with “Band Baaja Baaraat”. Actor Ranveer Singh, currently busy with Rohit Shetty’s “Simmba”, credits his career in the Hindi film industry to his love for masala entertainers.

Masala entertainers, are in fact, his “favourite” genre.

“Mainstream Hindi films, masala entertainers are the reason I ever wanted to become an actor. When I was a kid, I used to only watch these kind of films. It has been my education, it has been a part of my upbringing.

“So, it is a huge deal for me that I am finally doing something that is a true blue masala entertainer,” Ranveer told IANS in an e-mail interaction from Mumbai.

In “Simmba“, Ranveer will be seen playing a flamboyant policeman Sangram Bhalerao. He feels he has earned this opportunity.

“Having put in the work over few years, I’m getting to be a leading man in Rohit sir’s film. I regard him to be the finest proponent in the masala genre.

“He is the undisputed best in the business of masala entertainers. It could not be sweeter, it could not be better,” said the actor.

For the “Padmaavat” star, the entire “Simmba” team is like a close-knit family.

Click here : Entertainment News

Cheese your way to good health (Health Notes)

While there are several variants of cheese, one of the healthiest avatars called feta enriches your nourishment quotient. ‘Feta’ is derived from the Greek word for slice. Available in a soft texture, this white brined cheese which crumbles on touch is one the “healthiest cheeses in the world”.

Cheese is a very delicious complement to any kind of meal but sadly people avoid this calcium-rich food when sticking to a healthy diet. While most people love cheese, there seems to be a mental block. Here comes feta a cheese with great taste which is packed with good health. Let’s unveil this “packed with good health” cheese :

* Energy and lower fat content: Feta is low in calories and fat than most other cheeses.

According to Chef Priya Dikshit, “Due to it’s strong flavor, just one ounce as part of your meals is enough. This one-ounce serving contains 69 calories and only 5.9 grams of fat, of which 4.23 grams are saturated, while Cheddar has 9 gms of fat in a similar serving size”. Feta cheese contains up to 1.9 per cent conjugated linoleic acid (CLA) a fatty acid known to help improve body composition, decrease fat mass and increase lean body mass.

Read full story :- Health News