Turns out, blocking Cholecystokinin (CCK), a digestive hormone, can help in preventing pancreatic cancer.
In comparison to the recent research, previous ones have shown that obesity and high-fat diets both together as well as independently increase the risk of pancreatic cancer.
CCK is released by the small intestine and is associated with obesity. Dietary fat triggers the secretion of CCK and those who follow a diet high in saturated fats often have high levels of CCK.
CCK also regulates regeneration that takes place after partial surgical removal of the pancreas.
Pancreatic growth and regeneration occur through the interaction of CCK with CCK receptors, proteins that bind to CCK to produce a physiological reaction.
In separate studies conducted on mices involved the interactions between dietary fat, CCK, and pancreatic cancer cell growth.
In all studies, half the mice were fed a high-fat diet and the other half followed a normal diet.
In the first study, half of the animals were treated with proglumide, a medication that blocks CCK. In the second study, the mice had tumours lacking CCK. In the third study, the mice were deficient in CCK and had pancreatic tumours.
No comments:
Post a Comment